Sperm Associated Antigen 9 Plays an Important Role in Bladder Transitional Cell Carcinoma

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Sperm Associated Antigen 9 Plays an Important Role in Bladder Transitional Cell Carcinoma

BACKGROUND Majority of bladder cancer deaths are caused due to transitional cell carcinoma (TCC) which is the most prevalent and chemoresistant malignancy of urinary bladder. Therefore, we analyzed the role of Sperm associated antigen 9 (SPAG9) in bladder TCC. METHODOLOGY AND FINDINGS We examined SPAG9 expression and humoral response in 125 bladder TCC patients. Four bladder cancer cell lines...

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TRANSITIONAL CELL CARCINOMA OF THE BLADDER IN A 17 YEAR OLD MALE

Epithelial tumors are rarely seen during the first two decades of life. We report a 17 year old male with primary transitional cell carcinoma (TCC) of the bladder.

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Lymphoepithelial – Like Carcinoma with Papillary Transitional Cell Carcinoma of the Urinary Bladder Associated with Carcinoma in situ Changes of the Urothelium; A Case Report and Review of Literature

Lymphoepithelial - like carcinoma, is rarely recognized in the urinary bladder and less commonly occurs with papillary transitional cell carcinoma i.e. mixed pattern. Also, less uncommon is the occurrence of carcinoma in situ changes in the adjacent urothelium of these tumors. Here, a case of lymphoepithelial – like carcinoma and papillary transitional cell carcinoma associated with carci...

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Sperm-associated antigen 9 is associated with tumor growth, migration, and invasion in renal cell carcinoma.

Renal cell carcinoma (RCC) represents one of the most resistant tumors to radiation and chemotherapy. Current therapies for RCC patients are inefficient due to the lack of diagnostic and therapeutic markers. Our recent studies have suggested an association of sperm-associated antigen 9 (SPAG9) with ovarian carcinomas. In the present study, we investigated the clinical relevance of SPAG9 in RCC ...

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Growth, Migration, and Invasion in Renal Cell Carcinoma Sperm-Associated Antigen 9 Is Associated With Tumor

Renal cell carcinoma (RCC) represents one of the most resistant tumors to radiation and chemotherapy. Current therapies for RCC patients are inefficient due to the lack of diagnostic and therapeutic markers. Our recent studies have suggested an association of sperm-associated antigen 9 (SPAG9) with ovarian carcinomas. In the present study, we investigated the clinical relevance of SPAG9 in RCC ...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0081348